师资队伍

卢志，清华大学助理教授，特别研究员，博士生导师。2018年和2023年于清华大学自动化系/脑与认知科学研究院分别获学士和博士学位，2023-2025年从事博士后研究。主要学术方向为脑成像与解析、智能显微技术等，研究兴趣包括：1) 高维光场感知，全面获取时-空-角信息实现高速高分辨三维显微成像，建立了首次突破“时-空-角”约束的扫描光场(Cell, 2021; Nat Protoc 2022)、共聚焦扫描光场(Nat Biotechnol, 2024)等系列脑介观成像框架；2) 高效鲁棒重建，研究人工智能技术拓展显微图像与视频序列的速度、分辨率、鲁棒性等维度，提出了基于探索“相-空间”关联性的超分辨(Nat Methods, 2023)、三维重建(Nat Methods, 2025)、去噪、去散射(Nat Commun, 2021)等系列脑图像增强方法；3) 具身智能分析，理解大规模细胞群体规律，助力生命科学与基础医学机理活体验证，合作支撑了药物性炎症机制解析(J Hepatol, 2023)、微环境修复调控景观(Adv Sci, 2024)、细胞级胞葬网络路径(Sci Transl Med, 2025)等多项基础研究。公开发明专利30余项。入选福布斯中国U30科学榜(2023)、博士后创新人才支持计划(2023)、国家高层次青年人才（中组部“万人计划”青年拔尖人才）(2024)，获得世界人工智能大会最高奖SAIL(2022,2024)、瑞士乔诺法(Dimitris N. Chorafas Prize)青年研究奖(2024)、中国光学十大进展(2022)、国际基础科学大会前沿探索奖(2023)、中国电子学会/自动化学会/北京市优博(2023)等荣誉。

2018 – 2023 清华大学 自动化系/脑与认知科学研究院 工学博士

2014 – 2018 清华大学 自动化系 工学学士

2025至今 清华大学 心理与认知科学系 助理教授

2023 – 2025 清华大学 自动化系/脑与认知科学研究院 博士后

介观脑成像与解析

计算神经科学

多模态数据理解与智能分析

人工智能驱动的科学研究

（课题组长期招收博士后、博士/硕士研究生、科研助理和实习生。其中，科研助理和实习生面向本硕博各阶段学生，鼓励长期深度参与，能稳定实习6个月以上者优先。对以上方向感兴趣的同学请联系：luzhi@tsinghua.edu.cn）

中国生物物理学会 生物医学成像分会 副秘书长

国家疾控局 疾病预防控制领域“人工智能+”工作专班 成员

2025 清华大学优秀博士后（10 out of 3,500）

2024 中组部“万人计划”青年拔尖人才

2024 瑞士乔诺法（Dimitris N. Chorafas Prize）青年研究奖（全球~30人/年）

2024 世界人工智能大会卓越人工智能引领者奖（大会最高奖，SAIL Award，5项/年，排序1/1）

2024 世界人工智能大会青年优秀论文奖（WAIC YOP）

2023 国际基础科学大会Best Paper Award in Computational Optics

2023 福布斯中国U30科学榜

2023 国家博士后创新人才支持计划

2023 北京市优秀博士学位论文

2023 中国自动化学会研究生论文工程-博士论文一等学位论文

2023 中国电子学会博士学位论文激励计划

2023 清华大学研究生毕业典礼发言代表（1 out of 7,500）

2022 “中国光学十大进展”（应用研究类）

2022 清华大学学生年度人物（10 out of 45,000）

2022 清华大学研究生“学术新秀”（10 out of 30,000）

2021 “中国光学十大进展”提名奖（应用研究类）

2021 《科技导报》中国重大技术进展

2021 Cell Press中国年度论文

5篇代表性学术论文（^#共同一作，*通讯作者）：

1. Jiamin Wu^#; Zhi Lu^#; Dong Jiang^#; Yuduo Guo; Hui Qiao; Yi Zhang; Tianyi Zhu; Yeyi Cai; Xu Zhang; Karl Zhanghao; Hao Xie; Tao Yan; Guoxun Zhang; Xiaoxu Li; Zheng Jiang; Xing Lin; Lu Fang; Bing Zhou; Peng Xi; Jingtao Fan*; Li Yu*; Qionghai Dai*; Iterative tomography with digital adaptive optics permits hour-long intravital observation of 3D subcellular dynamics at millisecond scale. Cell, 2021, 184, 3318-3332. (SCI, 2021 IF 66.850)

   https://doi.org/10.1016/j.cell.2021.04.029

2. Zhi Lu^#; Yu Liu^#; Manchang Jin; Xin Luo; Huanjing Yue; Zian Wang; Siqing Zuo; Yunmin Zeng; Jiaqi Fan; Yanwei Pang; Jiamin Wu*; Jingyu Yang*; Qionghai Dai*; Virtual-scanning light-field microscopy for robust snapshot high-resolution volumetric imaging. Nature Methods, 2023, 20, 735-746. (SCI, 2023 IF 36.1)

   https://doi.org/10.1038/s41592-023-01839-6

3. Zhi Lu^#; Manchang Jin^#; Shuai Chen; Xiaoge Wang; Feihao Sun; Qi Zhang; Zhifeng Zhao; Jiamin Wu*; Jingyu Yang*; Qionghai Dai*; Physics-driven self-supervised learning for fast high-resolution robust 3D reconstruction of light-field microscopy. Nature Methods, 2025, 22, 1545-1555. (SCI, 2024 IF 32.1)

   https://doi.org/10.1038/s41592-025-02698-z

4. Zhi Lu^#; Siqing Zuo^#; Minghui Shi^#; Jiaqi Fan; Jingyu Xie; Guihua Xiao; Li Yu*; Jiamin Wu*; Qionghai Dai*; Long-term intravital subcellular imaging with confocal scanning light-field microscopy. Nature Biotechnology, 2025, 43, 569–580. (SCI, 2024 IF 41.7)

   https://doi.org/10.1038/s41587-024-02249-5

5. Zhi Lu; Yeyi Cai; Yixin Nie; Yuxin Yang; Jiamin Wu*; Qionghai Dai*; A practical guide to scanning light-field microscopy with digital adaptive optics. Nature Protocols, 2022, 17, 1953–1979. (SCI, 2022 IF 14.8)

   https://doi.org/10.1038/s41596-022-00703-9

其他学术论文（^#共同一作，*通讯作者，按时间倒序）：

2025 [6] Shuai Chen^#; Bingyuan Huang^#; Shanshan Li^#; Zhijing Wang^#; Yizhong Chang; Huaming Huang; Chun Liu; Shuo Zhang; Manchang Jin; Haoyu Jia; Bo Yang; Ziwen Tao; Li Chen; Kai Guo; Zhi Lu*; Jing Li*; Fei Wang*; Changqing Yang*; Myeloid Mas-driven macrophage efferocytosis promotes resolution in ischemia-stressed mouse and human livers. Science Translational Medicine, 2025, 17, eadr2725. (SCI, 2024 IF 14.6)

[7] Qicheng Zhuang, Xiaoqian Jin, Yizhong Chang, Huaming Huang, Ziwen Tao, Zhi Lu, Shuai Chen*, Changqing Yang*; Burden, Trends, and Projections of Alcohol-Associated Liver Disease and Alcohol Use Disorder in the Asia-Pacific Region 1990–2040. Liver International, 2025, 45, e70221. (SCI, 2024 IF 5.2)

[8] Qian Xiang^#; Yaqin Du^#; Zhukai Cong^#; Yutian Xiao; Zhi Lu; Mingjie Shao; Jian Xie*; Warifteine Alleviates ALI and Inhibits NETosis by Decreasing ROS-induced GSDMD Oligomerization. American Journal of Respiratory Cell and Molecular Biology, 2025. (SCI, 2024 IF 5.3) https://doi.org/10.1165/rcmb.2024-0472OC

[9] Fangfei Yu; Shaowei Jiang; Lishan Ye; Zhi Lu; Yiran Wang; Huijuan Wang; Yi Yang*; Confocal scanning light-field microscopy enables intravital visualization of remodeling hepatic immune microenvironment in chronic stress suffered mice. Fifth Optics Frontier Conference, 2025, 13648. (EI)

2024 [10] Shuai Chen^#; Zhi Lu^#; Yudong Zhao^#; Lu Xia^#; Chun Liu; Siqing Zuo; Manchang Jin; Haoyu Jia; Shanshan Li; Shuo Zhang; Bo Yang; Zhijing Wang; Jing Li*; Fei Wang*; Changqing Yang*; Myeloid-Mas Signaling Modulates Pathogenic Crosstalk among MYC⁺CD63⁺ Endothelial Cells, MMP12⁺ Macrophages and Monocytes in Acetaminophen-Induced Liver Injury. Advanced Science, 2024, 11, 202306066. (SCI, 2024 IF 14.1)

[11] Xin Luo^#; Zhi Lu^#,*; Manchang Jin; Shuai Chen; Jingyu Yang*; Efficient high-resolution fluorescence projection imaging over an extended depth of field through optical hardware and deep learning optimizations. Biomedical Optics Express, 2024, 15, 3831-3847. (SCI, 2024 IF 3.2)

[12] Xin Luo^#; Gaosheng Liu^#; Zhi Lu; Kun Li; Jingyu Yang*; Efficient Low-Light Light Field Enhancement With Progressive Feature Interaction. IEEE Transactions on Emerging Topics in Computational Intelligence, 2024. (SCI, 2024 IF 6.5)

[13] Yifan Chen^#, Jiamin Wu^#,*, Bo Xiong^#, Zhi Lu, Yuduo Guo, Yi Zhang, Jiaqi Fan, Guihua Xiao, Guoxun Zhang, Xiaopeng Li, Xukang Wang, Zhifeng Zhao; Qionghai Dai*; High-speed in toto 3D imaging with isotropic resolution by scanning light-field tomography. Optica, 2024, 11, 1445-1453. (SCI, 2024 IF 8.5)

[14] Tianyi Zhu^#; Lina Liu^#; Yibo Sun; Zhi Lu; Yuanlong Zhang; Chao Xu; Jun Chen*; Semi-supervised noise-resilient anomaly detection with feature autoencoder. Knowledge-Based Systems, 2024, 304, 112445. (SCI, 2024 IF 7.6)

[15] Zhi Lu*; Jiamin Wu*; Qionghai Dai*; Combining line confocal and scanning light field microscopy to achieve high-resolution observations in deep tissues. Imaging Systems and Applications, 2024, JM4A. (EI)

[16] Shuo Zhang; Xiaoqi Xia; Bing Ji; Yizhong Chang; Bo Yang; Haoyu Jia; Shuai Chen; Zhi Lu; Lu Xia; Jing Li; Changqing Yang*; IDDF2024-ABS-0027 The prognostic value of serum metabolites in predicting hepatic decompensation among patients with cirrhosis. Gut, 73(Suppl 2), 2024, A237-A239. (EI)

[17] Shuai Chen*; Changqing Yang; Zhi Lu; WED-017-YI Myeloid Mas-dependent macrophage efferocytosis maintains immune homeostasis in the ischemia-stressed mouse and human livers. Journal of Hepatology, 80, S362-S363, 2024. (EI)

[18] Shuai Chen; Zhi Lu; Changqing Yang*; Tu1587 Myeloid Mas Signaling Regulates Macrophage Efferocytosis and Resolution in Ischemia-Stressed Mouse and Human Liver. Gastroenterology, 166 (5), S-1741-S-1742, 2024. (EI)

2023 [19] Shuai Chen^#; Zhi Lu^#; Haoyu Jia^#; Bo Yang^#; Chun Liu; Yuxin Yang; Shuo Zhang; Zhijing Wang; Liu Yang; Shanshan Li; Jing Li* and Changqing Yang*. Hepatocyte-specific Mas activation enhances lipophagy and fatty acid oxidation to protect against acetaminophen-induced hepatotoxicity. Journal of Hepatology, 2023, 78, 543-557. (SCI, 2023 IF 26.8)

[20] Zhifeng Zhao^#; Yiliang Zhou^#; Bo Liu^#; Jing He^#; Jiayin Zhao; Yeyi Cai; Jingtao Fan; Xinyang Li; Zilin Wang; Zhi Lu; Jiamin Wu*; Hai Qi*; Qionghai Dai*; Two-photon synthetic aperture microscopy for minimally invasive fast 3D imaging of native subcellular behaviors in deep tissue. Cell, 2023, 186, 2475-2491. (SCI, 2023 IF 45.5)

[21] Zhi Lu*; Jiamin Wu; Qionghai Dai; Virtual-scanning network for high-resolution light-field microscopy. In Third International Computing Imaging Conference (CITA), 2023, 12921, 62-63. (EI)

[22] Shuai Chen; Zhi Lu; Shanshan Li; Huaming Huang; Jing Li; Changqing Yang*; IDDF2023-ABS-0045 Spatiotemporal immune landscape of Mas-driven pro-inflammatory microenvironment with hyperactivated glycolysis in acetaminophen-induced liver injury. Gut, 72(Suppl 1), 2023, A25-A28. (EI)

2022 [23] Jiamin Wu^#; Yuduo Guo^#; Chao Deng^#; Anke Zhang; Hui Qiao; Zhi Lu; Jiachen Xie; Lu Fang*; Qionghai Dai*; An integrated imaging sensor for aberration-corrected 3D photography, Nature, 2022, 612, 62-71. (SCI, 2022 IF 64.8)

[24] Yi Zhang^#; Yuling Wang^#; Mingrui Wang; Yuduo Guo; Xinyang Li; Yifan Chen; Zhi Lu; Jiamin Wu*; Xiangyang Ji*; Qionghai Dai*; Multi-focus light-field microscopy for high-speed large-volume imaging. PhotoniX, 2022, 3, 1-20. (SCI, 2022 IF 16.5)

[25] Tianyi Zhu^#; Yuduo Guo^#; Yi Zhang; Zhi Lu; Xing Lin; Lu Fang; Jiamin Wu*; Qionghai Dai*; Noise-robust phase-space deconvolution for light-field microscopy. Journal of Biomedical Optics, 2022, 27, 076501. (SCI, 2022 IF 3.5)

2021 [26] Yi Zhang^#; Zhi Lu^#; Jiamin Wu^#,*; Xing Lin; Dong Jiang; Yeyi Cai; Jiachen Xie; Yuling Wang; Tianyi Zhu; Xiangyang Ji*; Qionghai Dai*; Computational optical sectioning with an incoherent multiscale scattering model for light-field microscopy. Nature Communications, 2021, 12, 6391. (SCI, 2021 IF 17.694)

[27] Yuanlong Zhang^#; Bo Xiong^#; Yi Zhang; Zhi Lu; Jiamin Wu*; Qionghai Dai*; DiLFM: an artifact-eliminated and noise-robust light-field microscopy through dictionary learning. Light: Science & Applications, 2021, 10, 152. (SCI, 2021 IF 20.257)

2020 [28] Zhi Lu; Yi Zhang; Tianyi Zhu; Tao Yan; Jiamin Wu; Qionghai Dai*; High-speed 3D observation with multi-color light field microscopy. Microscopy Histopathology and Analytics, 2020, MM2A. (EI)

2019 [29] Zhi Lu; Jiamin Wu; Hui Qiao; You Zhou; Tao Yan; Zijing Zhou; Xu Zhang; Jingtao Fan; Qionghai Dai*; Phase-space deconvolution for light field microscopy. Optics Express, 2019, 27, 18131-18145. (SCI, 2019 IF 3.669)

[30] Zhi Lu; Jiamin Wu; Hui Qiao; Tao Yan; Zijing Zhou; Xu Zhang; Jingtao Fan; Qionghai Dai*; Artifact-free 3D deconvolution for light field microscopy. Novel Techniques in Microscopy, 2019, NS1B. (EI)

[31] Xiaoxu Li; Hui Qiao; Jiamin Wu; Zhi Lu; Tao Yan; Ruxin Zhang; Xu Zhang; Qionghai Dai*; DeepLFM: Deep learning-based 3d reconstruction for light field microscopy. Novel Techniques in Microscopy, 2019, NM3C. (EI)

2018 [32] Jijun He; Jiamin Wu; Zhi Lu; Qionghai Dai*; Compressive hyperspectral imaging for snapshot multi-channel fluorescence microscopy. Computational Optical Sensing and Imaging, 2018, CW2E. (EI)

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