师资队伍

卢志，清华大学助理教授，特别研究员，博士生导师，国家高层次青年人才，担任Cogni Lab (Computational Optics Guided Neural Intelligence Lab) 实验室负责人。于清华大学自动化系/脑与认知科学研究院获学士和博士学位，师从戴琼海院士。主要学术方向为计算成像、智能显微、认知计算、具身学习、科学智能等。以(共同)第一/通讯作者身份发表Cell 1篇，Nature子刊10篇，Science子刊2篇。研究兴趣包括：(1) 高维光场感知，全面获取时-空-角信息实现高速高分辨三维显微成像，建立了首次突破“时-空-角”约束的扫描光场(Cell 2021; Nat Protoc 2022)、共聚焦扫描光场(Nat Biotechnol 2024)、高NA介观活体显微(Nat Biotechnol 2026a)等系列计算成像框架；(2) 高效鲁棒重建，研究人工智能技术拓展显微图像与视频序列的速度、分辨率、鲁棒性等维度，提出了基于探索“相-空间”关联性的超分辨(Nat Methods 2023)、三维重建(Nat Methods 2025)、去噪(Nat Commun 2025; Sci Adv 2026)、去像差(Nat Biotechnol 2026b)、去散射(Nat Commun 2021)、运动补偿(Nat Commun 2026)等系列图像处理方法；(3) 认知智能解码，理解大规模细胞群体规律，助力生命科学与基础医学机理活体验证，合作支撑了药物性炎症机制解析(J Hepatol 2023; Cell Mol Immunol 2025)、微环境修复调控景观(Adv Sci 2024)、细胞级胞葬网络路径(Sci Transl Med 2025)等多项生命医药研究。授权发明专利30余项。入选福布斯中国U30科学榜(2023)、博士后创新人才支持计划(2023)、国家高层次人才特殊支持计划青年拔尖人才项目(2024)、福布斯·环球联盟国际化青年领袖(2026)，获得世界人工智能大会最高奖SAIL(2022,2024)、瑞士乔诺法(Dimitris N. Chorafas Prize)青年研究奖(2024)、中国光学十大进展(2022)、国际基础科学大会前沿探索奖(2023)、中国电子学会/自动化学会/北京市优博(2023)等荣誉。

2018 – 2023 清华大学 自动化系/脑与认知科学研究院 工学博士

2014 – 2018 清华大学 自动化系 工学学士

2025至今, 清华大学 心理与认知科学系 助理教授

2025至今, 清华大学 自动化系(智能科学与技术专业) 兼聘教研系列教师

2023 - 2025, 清华大学 自动化系/脑与认知科学研究院 博士后

生物、医学光学与光子学

计算成像与智能显微

多任务显微图像处理大模型

多模态数据理解大模型

计算神经科学

认知计算

具身智能与脑启发世界模型

人工智能驱动的科学研究

（实验室长期招收博士后、博士/硕士研究生、科研助理和实习生，提供稳定的科研补助。其中，科研助理和实习生面向本硕博各阶段学生，充分支持其他高校/院系在读硕博生进行交流合作，鼓励长期深度参与，高度支持远程进行，能稳定投入6个月以上者优先。对以上方向感兴趣的同学欢迎与我联系：luzhi@tsinghua.edu.cn）

中国生物物理学会 生物医学成像分会 副秘书长

中国电子学会 信号处理分会 委员

国家疾控局 疾病预防控制领域“人工智能+”工作专班 成员

2026 福布斯·环球联盟国际化青年领袖

2026 全国成像探测与信息处理学术会议优秀青年科技奖

2025 清华大学优秀博士后（10 out of 3,500）

2024 国家高层次人才特殊支持计划青年拔尖人才

2024 瑞士乔诺法（Dimitris N. Chorafas Prize）青年研究奖（欧洲最有影响力的青年学术奖励之一，全球~30人/年）

2024 世界人工智能大会卓越人工智能引领者奖（大会最高奖，SAIL Award，5项/年）

2024 世界人工智能大会青年优秀论文奖（WAIC YOP）

2023 国际基础科学大会Best Paper Award in Computational Optics

2023 福布斯中国U30科学榜

2023 国家博士后创新人才支持计划

2023 中国电子学会、自动化学会、北京市优秀博士学位论文

2023 清华大学研究生毕业典礼发言代表（1 out of 7,500）

2022 “中国光学十大进展”（应用研究类）

2022 清华大学学生年度人物（10 out of 45,000）

2022 清华大学研究生“学术新秀”（10 out of 30,000）

2021 “中国光学十大进展”提名奖（应用研究类）

2021 《科技导报》中国重大技术进展

2021 Cell Press中国年度论文

（#第一作者，*通讯作者）

2026

[1] Yunmin Zeng; Qi Zhang; Yihong Xiao; Shidong Wu; Seonghoon Kim; Yunhao Zhang; Mingrui Wang; Yuanlong Zhang; Xinyang Li; Zhi Lu*; Jiamin Wu*; Qionghai Dai*; High-fidelity intravital imaging of biological dynamics with latent-space-enhanced digital adaptive optics. Nature Biotechnology, 2026. (IF_5-year 50.9) https://doi.org/10.1038/s41587-026-03107-2

[2] Zhi Lu^#; Minghuan Wang^#; Wentao Chen^#; Manchang Jin; Laiyu Zhu; Tianyun Wang; Qi Zhang; Yi Yang; Chaowei Zhuang; Jiamin Wu*; Qionghai Dai*; High-numerical-aperture confocal volumetric mesoscope reveals mesoscale subcellular dynamics in vivo. Nature Biotechnology, 2026. (IF_5-year 50.9) https://doi.org/10.1038/s41587-026-03231-z

[3] Yuanjie Gu^#; Yiqun Wang^#; Ang Xuan; Jianping Wang; Linyi Wang; Lei Zhang; Xiaoran Li; Yao Wu; Jun Zhang; Zhi Lu*; Biqin Dong*; Enhancing Biomedical Optical Volumetric Imaging via Self-Supervised Orthogonal Learning. Science Advances, 2026. (IF_5-year 14.8) https://doi.org/10.1126/sciadv.ady9194

[4] Yuedi Wang^#; Jingyao Wu^#; Jiamin Wu; Yuan Li; Wenjin Lv; Fangfei Yu; Jun Yan; Zhi Lu*; Yi Yang*; Qionghai Dai*; Real-time robust autofocus method enabling sustained intravital scanning light field imaging. Nature Communications, 2026. (IF_5-year 18.9) https://doi.org/10.1038/s41467-026-74976-z

[5] Yixin Li; Qi Zhang; Yuanlong Zhang; Jiaqi Fan; Zhi Lu; Xinhong Xu; Xinyang Li*; Ziwei Li*; Jiamin Wu*; Qionghai Dai*; Unsupervised transfer learning enables multi-animal tracking without training annotation. Nature Methods, 2026. (IF_5-year 52.5) https://doi.org/10.1038/s41592-026-03051-8

[6] Yifan Chen; Yunmin Zeng; Tao Yu; Yuduo Guo; Yuwang Wang; Zhi Lu; Jiamin Wu*; Qionghai Dai*; Super-Snell scanning light-field display for ultra-wide-angle high-resolution glasses-free 3D displays. Nature Photonics, 2026. (IF_5-year 39.5) https://doi.org/10.1038/s41566-026-01938-8

2025

[7] Zhi Lu^#; Manchang Jin^#; Shuai Chen; Xiaoge Wang; Feihao Sun; Qi Zhang; Zhifeng Zhao; Jiamin Wu*; Jingyu Yang*; Qionghai Dai*; Physics-driven self-supervised learning for fast high-resolution robust 3D reconstruction of light-field microscopy. Nature Methods, 2025. (IF_5-year 52.5) https://doi.org/10.1038/s41592-025-02698-z

[8] Zhi Lu^#; Wentao Chen^#; Feihao Sun; Jiaqi Fan; Xinyang Li; Zhenqi Fu; Manchang Jin; Jiamin Wu*; Qionghai Dai*; Leveraging spatial-angular redundancy for self-supervised denoising of 3D fluorescence imaging without temporal dependency. Nature Communications, 2025. (IF_5-year 18.9) https://doi.org/10.1038/s41467-025-66654-3

[9] Shuai Chen^#; Bingyuan Huang^#; Shanshan Li^#; Zhijing Wang^#; Yizhong Chang; Huaming Huang; Chun Liu; Shuo Zhang; Manchang Jin; Haoyu Jia; Bo Yang; Ziwen Tao; Li Chen; Kai Guo; Zhi Lu*; Jing Li*; Fei Wang*; Changqing Yang*; Myeloid Mas-driven macrophage efferocytosis promotes resolution in ischemia-stressed mouse and human livers. Science Translational Medicine, 2025. (IF_5-year 16.8) https://doi.org/10.1126/scitranslmed.adr2725

[10] Yuanyuan Luo^#; Yarong Hao^#; Chunyan Sun^#; Zhi Lu^#; Hao Wang^#; Yuhan Lin; Yaping Guan; Lingyan Cai; Chenhong Ding; Binbin Li; Fei Chen; Yiting Lu; Yong Lin*; Xin Zeng*; Gut-derived indole propionic acid alleviates liver fibrosis by targeting pro-fibrogenic macrophage via gut-liver axis. Cellular & Molecular Immunology, 2025. (IF_5-year 27.6) https://doi.org/10.1038/s41423-025-01339-x

2024

[11] Zhi Lu^#; Siqing Zuo^#; Minghui Shi^#; Jiaqi Fan; Jingyu Xie; Guihua Xiao; Li Yu*; Jiamin Wu*; Qionghai Dai*; Long-term intravital subcellular imaging with confocal scanning light-field microscopy. Nature Biotechnology, 2024. (IF_5-year 50.9) https://doi.org/10.1038/s41587-024-02249-5

[12] Shuai Chen^#; Zhi Lu^#; Yudong Zhao^#; Lu Xia^#; Chun Liu; Siqing Zuo; Manchang Jin; Haoyu Jia; Shanshan Li; Shuo Zhang; Bo Yang; Zhijing Wang; Jing Li*; Fei Wang*; Changqing Yang*; Myeloid-Mas signaling modulates pathogenic crosstalk among MYC⁺CD63⁺ endothelial cells, MMP12⁺ macrophages and monocytes in Acetaminophen-induced liver injury. Advanced Science, 2024. (IF_5-year 15.6) https://doi.org/10.1002/advs.202306066

2023

[13] Zhi Lu^#; Yu Liu^#; Manchang Jin; Xin Luo; Huanjing Yue; Zian Wang; Siqing Zuo; Yunmin Zeng; Jiaqi Fan; Yanwei Pang; Jiamin Wu*; Jingyu Yang*; Qionghai Dai*; Virtual-scanning light-field microscopy for robust snapshot high-resolution volumetric imaging. Nature Methods, 2023. (IF_5-year 52.5) https://doi.org/10.1038/s41592-023-01839-6

[14] Shuai Chen^#; Zhi Lu^#; Haoyu Jia^#; Bo Yang^#; Chun Liu; Yuxin Yang; Shuo Zhang; Zhijing Wang; Liu Yang; Shanshan Li; Jing Li*; Changqing Yang*; Hepatocyte-specific Mas activation enhances lipophagy and fatty acid oxidation to protect against acetaminophen-induced hepatotoxicity. Journal of Hepatology, 2023. (IF_5-year 33.1) https://doi.org/10.1016/j.jhep.2022.10.028

[15] Zhifeng Zhao^#; Yiliang Zhou^#; Bo Liu^#; Jing He^#; Jiayin Zhao; Yeyi Cai; Jingtao Fan; Xinyang Li; Zilin Wang; Zhi Lu; Jiamin Wu*; Hai Qi*; Qionghai Dai*; Two-photon synthetic aperture microscopy for minimally invasive fast 3D imaging of native subcellular behaviors in deep tissue. Cell, 2023. (IF_5-year 50.7) https://doi.org/10.1016/j.cell.2023.04.016

2022

[16] Zhi Lu; Yeyi Cai; Yixin Nie; Yuxin Yang; Jiamin Wu*; Qionghai Dai*; A practical guide to scanning light-field microscopy with digital adaptive optics. Nature Protocols, 2022. (IF_5-year 20.5) https://doi.org/10.1038/s41596-022-00703-9

[17] Jiamin Wu^#; Yuduo Guo^#; Chao Deng^#; Anke Zhang; Hui Qiao; Zhi Lu; Jiachen Xie; Lu Fang*; Qionghai Dai*; An integrated imaging sensor for aberration-corrected 3D photography, Nature, 2022. (IF_5-year 56.7) https://doi.org/10.1038/s41586-022-05306-8

[18] Yi Zhang^#; Yuling Wang^#; Mingrui Wang; Yuduo Guo; Xinyang Li; Yifan Chen; Zhi Lu; Jiamin Wu*; Xiangyang Ji*; Qionghai Dai*; Multi-focus light-field microscopy for high-speed large-volume imaging. PhotoniX, 2022. (IF_5-year 18.1) https://doi.org/10.1186/s43074-022-00076-y

2021

[19] Jiamin Wu^#; Zhi Lu^#; Dong Jiang^#; Yuduo Guo; Hui Qiao; Yi Zhang; Tianyi Zhu; Yeyi Cai; Xu Zhang; Karl Zhanghao; Hao Xie; Tao Yan; Guoxun Zhang; Xiaoxu Li; Zheng Jiang; Xing Lin; Lu Fang; Bing Zhou; Peng Xi; Jingtao Fan*; Li Yu*; Qionghai Dai*; Iterative tomography with digital adaptive optics permits hour-long intravital observation of 3D subcellular dynamics at millisecond scale. Cell, 2021. (IF_5-year 50.7) https://doi.org/10.1016/j.cell.2021.04.029

[20] Yi Zhang^#; Zhi Lu^#; Jiamin Wu^#,*; Xing Lin; Dong Jiang; Yeyi Cai; Jiachen Xie; Yuling Wang; Tianyi Zhu; Xiangyang Ji*; Qionghai Dai*; Computational optical sectioning with an incoherent multiscale scattering model for light-field microscopy. Nature Communications, 2021. (IF_5-year 18.9) https://doi.org/10.1038/s41467-021-26730-w

[21] Yuanlong Zhang^#; Bo Xiong^#; Yi Zhang; Zhi Lu; Jiamin Wu*; Qionghai Dai*; DiLFM: an artifact-eliminated and noise-robust light-field microscopy through dictionary learning. Light: Science & Applications, 2021. (IF_5-year 24.0) https://doi.org/10.1038/s41377-021-00587-6

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